Clinical Research on Bowel Symptoms of Patient With Pelvic Organ Prolapse

N/AUnknownNCT02731391

Peking University People's Hospital200 enrolled

Overview

To study the prevalence of bowel symptoms in patients with pelvic organ prolapse.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

200

Conditions

Bowel Symptoms

Interventions

Pelvic floor reconstruction（with or without mesh）PROCEDURE

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * The patients with stage\>2 POP are recruited.The patients are all received surgeries, which include transvaginal synthetic mesh surgery, the sacral fixation, tissue repair surgery and colpocleisis. Exclusion Criteria: * Gestation； * Inflammatory bowel disease； * Slow transit constipation diagnosed by Colonic transit test； * Unable to follow up.

Locations (1)

Peking University People's Hospital

Beijing, Beijing Municipality, China

RECRUITING

Outcomes

Primary Outcomes

change in the prevalence of bowel symptoms

Time frame: baseline,1,3,6,12 months after operation.

change in the severity of intestinal symptoms

assessed by Birmingham Bowel and Urinary Symptoms Questionnaire

Time frame: baseline,1,3,6,12 months after operation.

Secondary Outcomes

change in the quality of life

assessed by international consultation on incontinence questionnaire short form

Time frame: baseline,1,3,6,12 months after operation.

length of the high-pressure zone recorded by anorectal manometry

Time frame: baseline and 12 months after operation

rectoanal inhibitory reflex recorded by anorectal manometry

Time frame: baseline and 12 months after operation

Rectal-Vaginal pressure interval during maximum Vasalva

Measured by Peritron manometer

Time frame: baseline and 6 months after operation

Data from ClinicalTrials.gov

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