Nowadays, TRUS biopsy become one of the most popular tests for diagnosis of prostate cancer. This procedure causes pain to the patients who does not received the sedative drugs or analgesic drugs. There are many ways to reduce pain and inconvenience for the patients, such as intravenous propofol, intravenous fentanyl etc. In Siriraj hospital, anesthesiologists usually give intravenous propofol with intravenous opioids but the visual analogue score after this procedure was average at 0.9-2.9. Furthermore, some systematic reviews have shown that there was no difference in pain score between periprostatic nerve block plus opioid and periprostatic nerve block only. So, this study is to find out whether opioids is need for TRUS biopsy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
124
normal saline IV
fentanyl 0.5 mcg/kg ideal BW
propofol infusion
Sirilak Suksompong
Bangkok, Thailand
Pain assess using Numeric rating scale (NRS) score
Time frame: 20 minutes
Number of participants with hypoxia defined as oxygen saturation <92%
The investigators define hypoxia as oxygen saturation \< 92%. The investigators will report as number of episode.
Time frame: 60 minutes
Number of participants with hypotension, defined as systolic blood pressure <90 mmHg
The investigators define hypotension as systolic blood pressure\< 90 mmHg. The investigators will report as number of episode.
Time frame: 60 minutes
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