Zero ischemia laparoscopic radio frequency ablation assisted tumor enucleation has been proved to enable tumor excision with relatively better renal function preservation comparing with conventional laparoscopic partial nephrectomy for T1a renal cell carcinoma (RCC) in a randomized clinical trial in single center. The investigators want to explore this technique to T1 RCC patients in randomized clinical trial in multiple centers.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
600
renal artery will be clamped during surgery.
Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University
Shanghai, China
RECRUITINGthe change in glomerular filtration rate (GFR) of the affected kidney
Time frame: Baseline and 30 months
changes of estimated GFR (eGFR)
Time frame: Baseline and 30 months
estimated blood loss
Time frame: during surgery
rates of positive surgical margin
Time frame: postoperative，up to 2 weeks after surgery
postoperative complications
Time frame: postoperative，up to 30 days
the rate of local recurrence
Time frame: through study completion, an average of 3 years
operative time
Time frame: During surgery
Hospital stay time
Time frame: The time from the surgery day to patient discharge, up to 2 weeks
progression-free survival rate
Time frame: through study completion, an average of 3 years
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