Study to Evaluate Multiple Doses in Patients With Nasal Polyposis

Inclusion Criteria: * TPS of ≥5 for both nostrils with presence on endoscopy of nasal polyps of grade ≥2 in each nostril according to the polyp grading scale * History of sinusitis symptoms * SNOT-22 ≥30 * No clinically significant Screening 12-lead ECG, vital sign, hematology, chemistry, or urinalysis findings Exclusion Criteria: * Use of systemic corticosteroids within 6 weeks of screening * Chronic use of antibiotic therapy within 3 months prior to Screening * Nasal surgery (including polypectomy) within 6 months prior to Screening * Use of investigational drugs or participation in another clinical trial within 30 days prior to Screening or 5 half-lives, whichever is longer