Cardiac REgistry of Celution Device for the Processing of Adipose-derived Regenerative Cells

Inclusion Criteria: * Males or females \> 20 and \< 80 years of age * Significant multi-vessel coronary artery disease not amenable to percutaneous or surgical revascularization OR idiopathic dilated cardiomyopathy * Symptoms of heart failure (e.g. NYHA Stages of Heart Failure Class II or III) * On maximal medical therapy for heart failure and if present, anginal symptoms * Hemodynamic stability (SBP ≥ 90 mm/Hg, HR \<110 beats/min) * Ejection fraction ≤ 45% * Left ventricular wall thickness \> 5 mm at the target site(s) for cell injection, confirmed by Contrast Echo within 4 weeks prior to enrollment, and free of thrombus Exclusion Criteria: * Vascular anatomy and/or peripheral artery disease that prevents or impedes cardiac catheterization * Aortic or mitral valve disease where valve replacement is indicated * Presence of mechanical aortic or mitral valves * Presence of aortic dissection * Planned staged treatment of CAD or other therapeutic intervention on the heart within the subsequent 3 months * TIA or stroke within 30 days prior to the procedure * ICD placement or ablation therapy within 30 days prior to the procedure * Acute coronary syndrome (ACS) or a myocardial infarction in the 30 days prior to the procedure * Revascularization within 30 days prior to intramyocardial injection of ADRCs * Pregnant or lactating status. Pregnancy as determined by a positive pregnancy test at screening or baseline.