Tranexamic Acid in Hip Fracture Surgery

Corewell Health West142 enrolled

Overview

To determine if TXA utilization is effective at reducing transfusion rates in elderly patients undergoing surgery for treatment of a hip fractures.

Study Type

OBSERVATIONAL

Enrollment

142

Conditions

Hip Fracture

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Acute, isolated, unilateral femoral neck, intertrochanteric, and per trochanteric hip fractures confirmed by anteroposterior/lateral hip radiographs, computed tomography, or magnetic resonance imaging. * Age 65 and older * Low energy mechanism of injury * Hip fracture fixation performed within 48 hours * English speaking * Anticipated medical optimization for operative fixation * No other major trauma Exclusion Criteria: * Retained hardware around the affected hip * Infection around the affected hip * Transfer patients with a length of stay \> 24 hours at the transferring hospital * Diagnosis of deficient natural anticoagulation * Known congenital thrombophilia (Deficiency of Protein C, S, Antithrombin) * Known allergy to TXA * Patients undergoing percutaneous pinning of the hip fracture

Outcomes

Primary Outcomes

Blood Transfusion Rate

Blood transfusion rates during the patients hospital stay will be assessed.

Time frame: 6 weeks

Secondary Outcomes

Hospital Length of stay

The patients length of stay in the hospital will be determined.

Time frame: 6 weeks

Post operative complications

Post operative complications will be assessed through the 6 weeks.

Time frame: 6 weeks

Hospitalization costs

Economic evaluation for inpatient and re-admission will be assessed.

Time frame: 6 weeks

Data from ClinicalTrials.gov

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