The aim of this study is to evaluate the effect of PIP toothbrush cleaner® on the microbial composition and Candida albicans colonization of denture biofilm formation. Additionally, its effect will be compared to that of cleansing tablets.
Therefore the present study intended to compare a probiotic denture cleaning protocol with the current protocols. It was aimed to examine, in institutionalized older individuals with removable complete dentures, if the microbial composition and C. albicans colonization of the denture biofilm differs when overnight stored in a probiotic cleaning product compared to water or a cleanser. Additionally the influence of brushing on these protocols was investigated.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Enrollment
13
Probiotic
Cleansing tablet -Corega Tabs Anti-bacteria® (GlaxoSmithKline Consumer Healthcare SA, Genval, Belgium)
Water
Department of Oral Health Sciences
Leuven, Belgium
Candida albicans colonization
C. albicans colonization was the primary outcome measure of interest. With a microbial test there was researched if C. albicans colonized the prostheses.
Time frame: day 5
Other microbiological counts Aa
The concentration of Aggregatibacter Actinomycetemcomitans was researched.
Time frame: day 5
Other microbiological counts Pg
The concentration of Porphyromonas gingivalis was researched.
Time frame: day 5
Other microbiological counts Tf
The concentration of Tannerella forsythensis was researched.
Time frame: day 5
Other microbiological counts Td
The concentration of Treponema denticola was researched.
Time frame: day 5
Other microbiological counts Pi
The concentration of Prevotella intermedia was researched.
Time frame: day 5
Other microbiological counts Fn
The concentration of Fusobacterium nucleatum was researched.
Time frame: day 5
Other microbiological counts Pm
The concentration of Peptostreptococcus micros was researched.
Time frame: day 5
Other microbiological counts Pn
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The concentration of Prevotella nigrescens was researched.
Time frame: day 5
Other microbiological counts Cg
The concentration of Campylobacter gracilis was researched.
Time frame: day 5
Other microbiological counts Cr
The concentration of Campylobacter rectus was researched.
Time frame: day 5
Other microbiological counts En
The concentration of Eubacterium nodatum was researched.
Time frame: day 5
Other microbiological counts Ec
The concentration of Eikenella corrodens was researched.
Time frame: day 5
Other microbiological counts Capn
The concentration of Capnocytophaga species was researched.
Time frame: day 5
Other microbiological counts Cc
The concentration of Campylobacter concisus count was researched.
Time frame: day 5
Other microbiological counts mitis streptococci
Concentration of mitis streptococci
Time frame: day 5
Other microbiological counts Sg
The concentration of Streptococcus gordonii
Time frame: day 5
Other microbiological counts Sc
The concentration of Streptococcus constellatus.
Time frame: day 5
Other microbiological counts Ao
The concentration of Actinomyces odontolyticus.
Time frame: day 5
Other microbiological counts Av
The concentration of Actinomyces viscosus.
Time frame: day 5
Other microbiological counts Vp
The concentration of Veillonella parvula.
Time frame: day 5
Other microbiological counts total
Total bacterial count.
Time frame: day 5