Background. Atrial fibrillation is one of the most common complications in the postoperative period of coronary artery bypass grafting (CABG) surgery and usually associated with increased length of hospital stay and higher hospital costs. Among the main mechanisms involved, excessive sympathetic activation, oxidative stress and inflammation are fundamental elements in the pathophysiology of obstructive sleep apnea. Objectives. To evaluate the effects of continuous positive airway pressure (CPAP) in reduction of atrial fibrillation after CABG in patients with obstructive sleep apnea. Methodological procedures: A multicenter randomized controlled study to compare the incidence of atrial fibrillation between the intervention group and the control group, both monitored seven days with Holter.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
144
patients will receive CPAP therapy with Auto-CPAP
Pronto Socorro Cardiológico de Pernambuco - Procape
Recife, Pernambuco, Brazil
Instituto de Medicina Integral Prof Fernando Figueira - Imip
Recife, Pernambuco, Brazil
INCOR - Instituto do Coração da Faculdade de Medicina da Universidade de São Paulo
São Paulo, São Paulo, Brazil
atrial fibrillation
will be verified by holter monitoring
Time frame: first 7 days after CABG
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.