The main purpose of this study is to measure the amount of study drug (BMS-986189) in the blood and urine and to see if BMS-986189 is safe and well-tolerated in healthy people after a single dose.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Enrollment
76
Covance Clinical Research Unit, Inc.
Evansville, Indiana, United States
Maximum observed concentration (Cmax)
Time frame: Day 1 to Day 30
Time of maximum observed concentration (Tmax)
Time frame: Day 1 to Day 30
Area under the concentration-time curve from time zero to the time of the last quantifiable concentration (AUC(O-T))
Time frame: Day 1 to Day 30
Area under the concentration-time curve from time zero extrapolated to infinite time (AUC(INF))
Time frame: Day 1 to Day 30
Half Life (T-HALF)
Time frame: Day 1 to Day 30
Total Body Clearance (CLT/F)
Time frame: Day 1 to Day 30
Apparent volume of distribution at steady state (Vss/F)
Time frame: Day 1 to Day 30
Deaths leading to discontinuation
Time frame: Day 1 to Day 30
Adverse events (AEs) leading to discontinuation
Time frame: Day 1 to Day 30
Serious adverse events (SAEs) leading to discontinuation
Time frame: Day 1 to Day 30
Lab abnormalities leading to discontinuation
Time frame: Day 1 to Day 30
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.