The purpose of this study is to compare the effects of dual acupoints and single acupoint transcutaneous electrical acupoint stimulation (TEAS) pretreatment on incidence of Post-Mastectomy Pain Syndrome(PMPS) in patients undergoing operation of breast cancer.
Patients were randomly assigned to three groups, receiving 30min TEAS before anesthesia respectively. The acupoints of dual point group are bilateral Neiguan points(PC6) combined with Danzhong point(RN17), single point group is bilateral Neiguan points(PC6), and the false stimulation group only attach electrodes without electric current. The frequency of TEAS is set to 2/15 Hz. Intraoperative anesthetic dosage of propofol and remifentanil was recorded. Three and six months after surgery, follow-up about chronic pain was made by telephone or face-to-face using the follow-up questionnaire. The adverse events were recorded.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
593
Electric stimulation was given through electrode attached to acupoints
patients were only attached electrodes without electric current
First Afiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China
People's hospital of Zhengzhou University
Zhengzhou, Henan, China
First Afiliated Hospital of Zhengzhou University
Zhengzhou, Henan, China
Tangdu Hospital, Fourth Military Medical University
Xi'an, Shaanxi, China
Incidence of chronic pain six months after surgery
Time frame: six months after surgery
Incidence of chronic pain three months after surgery
Time frame: three months after surgery
Remifentanil consumption during the surgery
Time frame: from start of surgery to end of surgery, at an average of 2.5 hours
the time to the first verbal response
Time frame: end of the anesthetics infusion to patient's first response to verbal command,on an average of 30 minutes
the time to extubation
Time frame: end of the anesthetics infusion to extubation,on an average of 30 minutes
postoperative nausea and vomiting within 24 h after surgery
Time frame: end of surgery to 24 hours after surgery,on an average of 24 hours
respiratory depression within 24 hours after surgery
Time frame: end of surgery to 24 hours after surgery,on an average of 24 hours
patients' s satisfaction scores on analgesia within 24 hours after surgery
Time frame: end of surgery to 24 hours after surgery,on an average of 24 hours
Visual Analogue Scale scores within 24 hours after surgery
Time frame: end of surgery to 24 hours after surgery,on an average of 24 hours
demand of rescue analgesics within 24 hours after surgery
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First Afiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China
Xijing Hospital, Fourth Military Medical University
Xi'an, Shaanxi, China
Time frame: end of surgery to 24 hours after surgery,on an average of 24 hours
pain score at 3m after surgery
Time frame: three months after surgery
pain score at 6m after surgery
Time frame: six months after surgery