This is the proof of concept study with multi-modality approach (using intra-thecal bioactive peptides, stem cells, laser and transcranial IV laser and Median Nerve stimulation as adjuvants) in cases of brain death due to traumatic brain injury having diffuse axonal injury to document possibility of reversal of brain death (BD).
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
20
BQ-A Peptide Extract
Mesenchymal Stem Cells
Transcranial Laser Therapy
Anupam Hospital
Rudrapur, Uttarakhand, India
Reversal of brain death as noted in clinical examination or EEG
Time frame: 15 days
Cerebrospinal fluid (CSF) analysis of color consistency, cell counts, and microbial evaluation
To signify any signs of aseptic or bacterial meningitis
Time frame: 15 days
MRI analysis to analyze any changes in meninges
To signify any signs of aseptic or bacterial meningitis
Time frame: 15 days
Pulse
Time frame: 15 days
O2 saturation
Time frame: 15 days
Blood Pressure
Time frame: 15 days
Respiration changes
Time frame: 15 days
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Median Nerve Stimulator