Leucine Supplementation in Young Subjects Undergoing Resistance Training

University of Sao Paulo60 enrolled

Overview

Leucine supplementation could be useful to support muscle anabolism. This study aims to investigate the effects of leucine supplementation on muscle mass and muscle strength in young subjects undergoing resistance training.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Masking

QUADRUPLE

Enrollment

Conditions

Healthy Volunteers

Interventions

LeucineDIETARY_SUPPLEMENT

PlaceboDIETARY_SUPPLEMENT

Eligibility

Sex: MALEMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * training experience \> 12 months * no previous use of anabolic steroids * no diagnosed diseases or injuries at the time of recruitment * one-maximum repetition strength (1-RM) in leg press ≥ 3.5 and ≤ 5.0 times the body weight Exclusion Criteria: * use of creatine or beta-alanine supplements for the last 3 months * use of protein or aminoacids supplements for the last 1 month * engagement in specific dietary restrictions * engagement in competitive sports

Locations (1)

University of Sao Paulo

São Paulo, São Paulo, Brazil

Outcomes

Primary Outcomes

muscle cross-sectional area

B-mode ultrasound

Time frame: 12 weeks

Secondary Outcomes

muscle strength

One repetition maximum (1RM) on 45º leg press machine and Muscular Endurance Test on 45º leg press machine

Time frame: 12 weeks

Data from ClinicalTrials.gov

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