Efficacy of Risedronate in Patients With Painful Periprosthetic Resorption of the Hip Prothesis

Inclusion Criteria: * Male or female subjects, 18 years of age or older. * Written informed consent * Subjects with cemented or not cemented total hip prothesis (for primitive or secondary coxarthrosis) * Painful aseptic loosening * Subject has pain 4 or greater on a 10 point Visual Pain Rating scale * For subject woman of reproductive age, they must use reliable method(s) of contraception and/or abstinence, for the duration of therapeutic product exposure. Exclusion Criteria: * Subjects with septic loosening of hip prosthesis . Subjects with bilateral disease * Subjects with implant mobility associated with pre-operative and intraoperative loosening * Subjects under anti-osteoporotic treatment * Subjects having stopped a biphosphonate traetment for less than one year * Subjects with known allergy or sensitivity to any of the components in the study medication. * Subjects with Hypocalcemia * Females who are pregnant, breast-feeding, or planning a pregnancy during the study or who think that they may be pregnant at the start of the study, or females of childbearing potential who are unable or unwilling to use a reliable form of contraception during the study. * Subjects with severe kidney failure ( creatinine \< 30 ml/min)). * Subjects participation in another research study * Subjects with previous osteonecrosis of the jaw