Lutonix® Global AV Registry Investigating Lutonix Drug Coated Balloon for Treatment of Native and Synthetic AV Fistulae

Inclusion Criteria: 1. Male or non-pregnant, non-breastfeeding female ≥18 years of age; 2. Patient is willing to provide informed consent, and is willing to comply with the protocol-required follow up visits; 3. Native or synthetic (grafts) arteriovenous fistula located in the arm, including central veins, presenting with any clinical, physiological or hemodynamic abnormalities warranting angiographic imaging as defined in the K/DOQI guidelines; and 4. Lesion(s) can be treated with available Lutonix DCB device size matrix per current IFU. Exclusion Criteria: Patients will be excluded if ANY of the following conditions apply: 1. Patient is currently participating in an investigational drug or device study which has not yet reached its primary endpoint or was previously enrolled into this registry (i.e. Lutonix Global AV registry). 2. Patient has a non-controllable allergy to contrast; or 3. Patient has another medical condition that, which in the opinion of the Investigator, may confound the data interpretation of is associated with a life expectancy insufficient to allow for completion of patient registry procedure and follow up.