The Ability research project, funded in Italy within the Smart Cities and Smart Communities funding program (MInistry of University and Research, Operational Regional Programme, Lombardy, Axis 1, Operational Regional Programme - European Funding for Regional Development 2007-2013), aims at developing and testing the efficacy and the impact of a Personal Smart Health Community able to provide innovative trajectories for people with cognitive impairment, putting them at the core of a continuous and intertwining treatment and support from both formal (e.g. physicians) and informal (e.g. near relatives) caregivers, with special focus on home-based care. Within this framework of the Ability project the investigators test the efficacy of the home-based motor-cognitive rehabilitation program delivered with two different approaches: the Ability platform versus the usual care program
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
30
The Ability program is an at home participant-tailored and technology-enhanced platform a) delivering tablet-based intensive (five days/a week for six weeks) motor and cognitive activities; b) monitoring from remote vital and physical health parameters (i.e., weight, Heart Rate, O2 saturation, daily steps, sleep activity).
Usual care at home program (paper and pencil cognitive activities; promotion of physical activity according to healthcare professional's advice)
activities of daily living
Activities of Daily Living Inventory (ADCS/ADL)
Time frame: change from baseline after 8 weeks (aMCI/AD subjects)
behavioral symptoms
Neuropsychiatric Inventory (NPI) score
Time frame: change from baseline after 8 weeks (aMCI/AD subjects)
cognitive domain (long-term memory)
Free and Cued Selective Recall Test (FCSRT) score
Time frame: change from baseline after 8 weeks (aMCI/AD subjects)
cognitive domain (language)
Fluency score
Time frame: change from baseline after 8 weeks (aMCI/AD subjects)
cognitive domain (frontal-executive functions)
Trail Making Test (TMT) score
Time frame: change from baseline after 8 weeks (aMCI/AD subjects)
quality of life
Dementia Quality of Life (D-QoL) Instrument
Time frame: change from baseline after 8 weeks (aMCI/AD subjects)
coping strategies
Coping Orientation for Problems Experienced - Brief Version (Brief COPE)
Time frame: change from baseline after 8 weeks (aMCI/AD subjects)
global cognitive level
Montreal Cognitive Asssessment (MoCA) score
Time frame: change from baseline after 12 months (aMCI/AD subjects)
activities of daily living
Activities of Daily Living Inventory (ADCS/ADL)
Time frame: change from baseline after 12 months (aMCI/AD subjects)
conversion rate MCI versus AD
conversion rate score
Time frame: change from baseline after 12 months (aMCI subjects)
cognitive domain - long term memory
Free and Cued Selective Recall Test (FCSRT) score
Time frame: change from baseline after 12 months (aMCI/AD subjects)
cognitive domain - language
Fluency score
Time frame: change from baseline after 12 months (aMCI/AD subjects)
cognitive domain - frontal executive functions
Trail Making Test (TMT) score
Time frame: change from baseline after 12 months
quality of life
Dementia Quality of Life (D-QoL) Instrument
Time frame: change from baseline after 12 months
coping strategies
Coping Orientation for Problems Experienced - Brief Version (Brief COPE)
Time frame: change from baseline after 12 months
caregiver quality of life
Psychological Well-Being (PWB) scale
Time frame: change from baseline after 8 weeks and after 12 months
caregiver coping strategies
Coping Orientation for Problems Experienced - Brief Version (Brief COPE)
Time frame: change from baseline after 8 weeks and after 12 months
caregiver burden
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Caregiver Burden Inventory (CBI)
Time frame: change from baseline after 8 weeks and after 12 months
caregiver affect
Positive and Negative Affect Schedule (PANAS)
Time frame: change from baseline after 8 weeks and after 12 months