Effects of Multiple Concussions in Retired NHL Players

New York Institute of Technology6 enrolled

Overview

To investigate long term affects of multiple concussions on the cognition, balance, proprioception, and biomarkers in retired National Hockey League players

This research study will collect data for each subject in one single visit. During the visit the subject will be asked to consent to the study which is estimated to take approximately 10 minutes. A medical history will be obtained, taking approximately 15 minutes. Blood, urine, and cheek swabs will be collected for approximately 15 minutes. The PHQ-9, Becks Depression Inventory, Connors Adult ADHD Rating Scale (CAARS™), and Montreal Cognitive Assessment (MoCA) will be administered, these assessments combined are estimated to take 50 minutes. Lastly, patients will be asked to complete a Sensory Organization Test (SOT) which takes approximately 15 minutes. There are only licensed health professionals working on this project that will respect your privacy and conduct this trial following all HIPPA and clinical research guidelines.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Cognitive Deficits Proprioceptive Disorders

Interventions

Sensory Organization TestOTHER

Balance and proprioception test

BiomarkersGENETIC

Blood, urine, and saliva biomarkers

Conners' Adult ADHD Rating Scale (CAARS)OTHER

Adult ADHD rating scale

Eligibility

Sex: MALEMin age: 40 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Retired professional NHL player * History or reported concussion and concussion like symptoms Exclusion Criteria: * Any neurological condition * Non sport related head trauma

Locations (1)

NYIT

Old Westbury, New York, United States

Outcomes

Primary Outcomes

Cognition assessed with the Montreal Cognitive Assessment Scale

Montreal Cognitive Assessment Scale

Time frame: 10 minutes

Secondary Outcomes

Beck's Depression Inventory

A 21 question multiple choice self report inventory measuring the severity of depression

Time frame: 10 minutes

Adult Attention Deficit assessed with the Connors' Adult Attention Deficit Disorder Rating Scale

Connors' Adult Attention Deficit Disorder Rating Scale

Time frame: 10 minutes

Proprioception/Postural Stability assessed with the Sensory Organization Test

Sensory Organization Test

Time frame: 15 minutes

Human Interleukin-6 (IL-6)

Blood (20 cc), Urine (40 cc): Total volume for all proposed biomarkers Marker type: Inflammation

Time frame: 5 Minutes

Patient Health Questionnaire 9 (PHQ-9)

Self administered screening and diagnostic questionnaire for mental health disorders

Time frame: 5 minutes

Interleukin 7 (IL-7)

Blood (20 cc), Urine (40 cc): Total volume for all proposed biomarkers Marker Type: Inflammation

Time frame: 5 minutes

Human 8-hydroxy-2' -deoxyguanosine (8-OHdG)

Blood (20 cc), Urine (40 cc): Total volume for all proposed Marker Type: Oxidative stress on DNA

Data from ClinicalTrials.gov

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