Effects of Light and Exercise on Human Circadian Rhythms and Performance

Brigham and Women's Hospital8 enrolled

Overview

Both light and exercise are effective countermeasures for space and ground-based crews for circadian phase resetting and alertness levels. The investigators propose to test the combined effects of these two countermeasures to determine whether adding exercise to light stimuli will further improve circadian phase resetting and alertness.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

Conditions

Circadian Rhythm

Interventions

Light and exerciseBEHAVIORAL

Exposure to light and exercise

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy by history, physical exam, laboratory studies of blood and urine, and psychological screening * moderate-intensity exercise for at least 150 minutes per week Exclusion Criteria: * color blind * no prescription medications, except hormonal birth control in females

Locations (1)

Brigham and Women's Hospital

Boston, Massachusetts, United States

Outcomes

Primary Outcomes

Circadian Phase

Circadian Phase will be measured using the change in timing of the melatonin rhythm on different days of the protocol. Melatonin will be assayed in blood and/or saliva.

Time frame: 8 days

Secondary Outcomes

Subjective alertness

Subjective alertness will be measured using the change in values on standardized mood scales on different days of the protocol.

Time frame: 8 days

Data from ClinicalTrials.gov

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