This study aims to compare image-based characteristics of carotid walls between symptomatic side and the opposite side. The design of this study is phase IV, prospective observational study.
Atherosclerosis of craniocervical arteries are one of most important causes of stroke. Carotid artery is the most frequent site of atherosclerosis. Recent research in carotid artery covers not only morphology of lumen but also direct visualization of carotid plaque or vessel wall. Vulnerable carotid plaques share pathologic features of intra-plaque inflammation and hemorrhage. There have been reports about post-contrast SWI in the field of vascular imaging. We hypothesized SWI is so sensitive to gadolinium based contrast agent and hemorrhage that contrast-enhanced SWI can visualize vulnerable carotid plaque. The purpose of this study is to investigate gadolinium-enhanced SWI in detection of vulnerable carotid plaque and compare it with MP-RAGE and DANTE T1-SPACE. This can be used to guide proper treatment for stroke.
Study Type
OBSERVATIONAL
Enrollment
25
Asan Medical Center
Seoul, South Korea
Seoul St. Mary's Hospital
Seoul, South Korea
Detection rate of findings of vulnerable carotid plaque
Time frame: within 3 days after enrollment
Accuracy in delinating geometry of carotid inner lumen and outer wall
Diameter of inner lumen and outer wall; Area of inner lumen and outer wall
Time frame: within 3 days after enrollment
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