The objective of this trial is to determine whether an opioid-free general anesthetic (OFA) technique utilizing ketamine, dexmedetomidine, and lidocaine infusions can help reduce postoperative pain in opiate-dependent chronic pain patients (CPPs) undergoing spine surgery when compared with traditional opioid-containing techniques. It is expected that this OFA regimen will have a measurable reduction on postoperative opioid consumption and pain scores in CPPs.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
30
An opioid-free general anesthetic technique utilizing dexmedetomidine, ketamine, and lidocaine infusions
Traditional general anesthetic technique utilizing sufentanil, fentanyl or remifentanil
Royal University Hospital
Saskatoon, Saskatchewan, Canada
Quantified opioid-consumption
Time frame: 48 hours following surgery
Visual analogue scale (VAS) pain scores
Time frame: 48 hours following surgery
Time of stay in post-anesthetic care unit (PACU)
Time frame: up to 5 hours following surgery
Incidence of adverse events
Time frame: 48 hours following surgery
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