Exercise Training and Hepatic Metabolism in Overweight/Obese Adolescent

Universidad Santo Tomas120 enrolled

Overview

The HEPAFIT Study aims to examine whether a 6-months physical education program has benefits on hepatic metabolism and cardiovascular health as well as on selected physical fitness and mental health outcomes among adolescent overweight/obese from Bogota, Colombia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

120

Conditions

Obesity Metabolic Syndrome X Lipid Metabolism Disorders Body Composition, Beneficial Mental Health Wellness 1

Interventions

Low physical activity programBEHAVIORAL

Exercise will be performed at three sessions per week. All sessions will be supervised by a trained health or exercise professional.

High physical activity programBEHAVIORAL

Exercise will be performed at three sessions per week. All sessions will be supervised by a trained health or exercise professional.

Low and High physical activity programBEHAVIORAL

Exercise will be performed at three sessions per week. All sessions will be supervised by a trained health or exercise professional.

Eligibility

Sex: ALLMin age: 11 YearsMax age: 17 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Overweight or obesity status * 11-17 years old * Written informed consent * Interested in improving health and fitness Exclusion Criteria: * Any other conditions which, in opinion of the investigators, would adversely affect the conduct of the trial. * Clinical diagnosis of diabetes * Pregnancy * Drugs/alcohol abuse

Outcomes

Primary Outcomes

Change from Baseline in hepatic fat measured by controlled attenuation parameter values (FibroScan®)

Changes in hepatic fat fraction measured by controlled attenuation parameter after the 6 months intervention program