fMRI in Impulsivity

Inclusion criteria: * Healthy Controls: Volunteers (age 18-50 yrs) in generally good Psychiatric and non-Psychiatric medical health * Borderline Personality Disorder subjects: Research volunteers (age 18-50 yrs) who meet DSM-5 criteria for Borderline Personality Disorder Exclusion criteria: All Participants: * Current medications which affect the central nervous system or vascular activity, such as anti-depressants, anxiolytics, or blood-pressure medications * Positive urine drug screen for cocaine, opioids, amphetamine, and benzodiazepines * Positive breathalyzer test for alcohol * History of clinically significant neurologic disorders or head trauma with loss of consciousness greater than 30 minutes * Clinically significant non-psychiatric medical disorder requiring ongoing treatment. * Unwillingness or inability to sign a written informed consent form * Pregnancy as assessed by a urine test for ß-HCG at each visit * Medical or physical contraindications for participation based on medical history interview, labs, and physical exam * Metal fragments or other bodily metal (e.g., pacemaker, orthopedic prosthesis),claustrophobia, or any other condition that would put the subjects at risk for MRI scanning In addition, Healthy Controls excluded, if: * DSM-5 diagnoses of Personality Disorders (based on SCID-II) * DSM-5 diagnoses based on the SCID-I (including the eating disorders module) * History of arrest or incarceration In addition, Borderline Personality Disorder Subjects excluded if: * DSM-5 diagnoses * DSM-5 Personality Disorder other than Cluster B Personality disorders * Current psychoactive medications * Further exclusion criteria apply