Perioperative Heart Rate Variability Analysis in Realtime

Medical University of Vienna88 enrolled

Overview

This study will record patient electrocardiograms - as well as various other body signals (e.g., blood pressure, pulse wave, peripheral hemoglobin oxygen saturation) - as monitored routinely both during and immediately subsequent to surgical operations performed under general anesthesia. Through retrospective analysis of patients' heart rate variability (HRV), in concert with the other abovementioned parameters, the investigators seek to forward the development of novel mathematical models and tools for on-line detection of cardiovascular and autonomic dysfunction in the perioperative setting.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Individuality Perioperative/Postoperative Complications Heart Rate and Rhythm Disorders Surgical Complications From General Anesthesia

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing non-cardiac surgery under general anesthesia * Patients aged 18-80 years * Patients who are capable of giving informed consent Exclusion Criteria: * Patients \<18 or \>80 years of age * Patients with an active cardiac pace maker * Patients with an absent sinus rhythm in ECG * Patients presenting with a preexisting arrhythmia * Patients requiring postoperative ICU therapy * Patients with pheochromocytoma

Outcomes

Primary Outcomes

Heart rate variability

The analysis of heart rate variability (HRV) has been used to assess autonomic nervous system responses to therapeutic interventions, and to quantify risk in a wide variety of both cardiac and non-cardiac disorders when combined with other diagnostic tests - though HRV analysis has seen its greatest cardiologic use in post-myocardial infarction risk stratification and in assessing risk for arrhythmic events. HRV analysis has become widespread and relatively simple to perform - however, until now, these analyses have not been performed in detail in the perioperative period.

Time frame: During and immediately subsequent to surgery performed under general anesthesia