Functional dyspepsia (FD), which is one of the most common gastrointestinal disorders with high disease burden. Postprandial distress syndrome (PDS) is a common subtype of FD. Although the effectiveness of Chinese herbal formula of Xiang-sha-liu-jun granule (XSLJG) for alleviating PDS symptoms has been assessed in previous studies, more convinced evidence of randomized placebo-controlled study is needed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
216
The Xiang-sha-liu-jun granules comprises 10 herbs, Astragalus membranaceus (Huangqi) 15g, Codonopsis pilosula (Dangshen) 15 g, fructus aurantii (Zhiqiao) 15g, fructus amomi(Sharen) etc
the first hospital affiliated to Guangzhou university of Chinese medicine
Guangzhou, Guangdong, China
RECRUITINGWuhan integrated TCM and western medicine hospital
Wuhan, Hubei, China
RECRUITINGchange of postprandial discomfort severity Scale
Time frame: Postprandial Discomfort Severity Scale at baseline, 2 weeks, and 4 weeks during oral administration of medicine
global impression scale
Time frame: global impression scale at baseline, 2 weeks, and 4 weeks during oral administration of medicine
SF-36 questionnaire
Time frame: SF-36 questionnaire at baseline, 2 weeks, and 4 weeks during oral administration of medicine
gastric emptying
Gastric emptying is related with several hormones such as CCK and ghrelin.
Time frame: gastric emptying will be assessed at baseline and 4 weeks during oral administration of medicine
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.