Comparison of Deep Neuromuscular Block and Moderate Neuromuscular Block on Quality of Recovery in Patients Undergoing Robotic Gastrectomy

Yonsei University56 enrolled

Overview

The purpose of this study is to investigate and compare the postoperative quality of recovery between the deep neuromuscular blockade and moderate neuromuscular blockade during robotic gastrectomy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

General Anesthesia

Interventions

Deep neuromuscular blockadeDRUG

neuromuscular blockade will be performed using a continuous infusion of rocuronium. Post-tetanic count 1-2 will be maintained during surgery. After the end of surgery, sugammadex of 4 mg/kg will be administered to reverse neuromuscular blockade.

Moderate neuromuscular blockadeDRUG

neuromuscular blockade will be performed using a continuous infusion of rocuronium. Train-of-four 1-2 will be maintained during surgery. After the end of surgery, sugammadex of 2 mg/kg will be administered to reverse neuromuscular blockade.

Eligibility

Sex: ALLMin age: 19 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * adult patients aged 19-80 years who are scheduled for robotic gastrectomy Exclusion Criteria: * Neuromuscular disease * History of malignant hyperthermia * Significant renal or hepatic dysfunction * Allergy to sugammadex or rocuronium

Locations (1)

Department of Anesthesiology and Pain Medicine Anesthesia and Pain Research Institute Yonsei University

Seoul, South Korea

Outcomes

Primary Outcomes

Postoperative quality of recovery

The postoperative quality of recovery will be evaluated at 24 and 48 hours after the end of surgery by the investigator who are blinded to the group assignments.

Time frame: within 48 hours after the end of surgery.

Secondary Outcomes

Surgical condition

Surgical condition will be evaluated after the end of surgery by the investigator who are blinded to the group assignments.

Time frame: within 48 hours after the end of surgery

shoulder pain

shoulder pain will be evaluated after the end of surgery by the investigator who are blinded to the group assignments.

Time frame: within 48 hours after the end of surgery

abdominal pain

abdominal pain will be evaluated after the end of surgery by the investigator who are blinded to the group assignments.

Time frame: within 48 hours after the end of surgery

nausea and vomiting

nausea and vomiting will be evaluated after the end of surgery by the investigator who are blinded to the group assignments.

Time frame: within 48 hours after the end of surgery

Data from ClinicalTrials.gov

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