An Interocular Comparative Study of Unilateral Cataract

Sun Yat-sen University53 enrolled

Overview

The purpose of this cross-sectional study is to compare bilateral anterior segment parameters, macular thickness, and BCVA at 3 months after uncomplicated unilateral pediatric cataract extraction with primary IOL implantation to explore any possible interocular differences and their possible relationships.

Great advances have been made in managing pediatric cataracts during the last several decades; these advances have contributed to a decrease in the incidence of postoperative complications and improvement in visual outcomes.Early cataract removal and replacement with an intraocular lens (IOL) represent the most appropriate treatments to avoid irreversible amblyopia.Although screening and timely surgical intervention play a key role in improved best corrected visual acuity (BCVA) among pediatric patients with cataracts, determining the prognosis for an individual remains difficult, particularly for unilateral cataract. Few studies have focused on the interocular differences in ocular anatomic parameters other than axial length in unilateral pediatric cataract after surgery, the significance of which for the possible interocular visual functional difference remains unclear. Therefore, the investigators conducted this cross-sectional study to compare bilateral anterior segment parameters, macular thickness, and BCVA at 3 months after uncomplicated unilateral pediatric cataract extraction with primary IOL implantation to explore any possible interocular differences and their possible relationships.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Cataract

Eligibility

Sex: ALLMax age: 10 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Children with uncomplicated surgeries * Children who were younger than 10 years old * Children with unilateral total cataract Exclusion Criteria: * Premature birth * Microphthalmia * Micro-or Megalocornea * Keratoconus * Glaucoma * Traumatic or complicated cataracts * Vitreous and retinal diseases * Any previous surgeries

Locations (1)

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, Guangdong, China

Outcomes

Primary Outcomes

Interocular anatomical parameters in pediatric unilateral cataract patients measured by pentacam

The Parameters are measured by pentacam (Oculus Inc., Wetzlar, Germany), a rotating Scheimpflug camera.

Time frame: Baseline

Visual function in pediatric unilateral cataract patients measured by Teller Acuity Cards

The visual function is measured by Teller Acuity Cards (Stereo Optical Company, Inc., IL, USA).

Time frame: Baseline

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.