Coronary revascularization improves survival for patients with coronary artery disease. However,many patients are left with poor physical and mental health. Traditional cardiac rehabilitation involves moderate intensity continuous exercise (MICE). Alternatives to traditional cardiac rehabilitation programming may however provide superior understudied benefits to patients with poor physical and mental health. Nordic walking (NW) and high-intensity interval training (HIIT) are two examples of alternative programs for cardiac rehabilitation, which may provide superior physical and mental health benefits when compared to traditional MICE. The main purpose of this project is, therefore, to determine the short and long term physical and mental health benefits of alternative cardiac rehabilitation modalities, including NW and HIIT on exercise capacity, quality of life and depression after a 12-week program.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
135
Participants will complete supervised exercise sessions. Participants will attend on-site high-intensity interval training two times weekly for 12 weeks
Participants will complete supervised exercise sessions. Moderate-intensity continuous exercise training will follow cardiovascular rehabilitation guidelines. Participants will attend on-site moderate-intensity continuous exercise training two times weekly for 12 weeks.
Participants will complete supervised exercise sessions. Participants will attend on-site Nordic walking training two times weekly for 12 weeks
University of Ottawa Heart Insititue
Ottawa, Ontario, Canada
Exercise Capacity
Changes in exercise capacity from baseline to 12 weeks and baseline to 26 weeks are measured by the six-minute walk test
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Functional Fitness
Changes in functional fitness from baseline to 12 weeks and baseline to 26 weeks are measured by the Senior Fitness Test
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Aortic stiffness
Changes in aortic stiffness from baseline to 12 weeks and baseline to 26 weeks are measured by pulse wave velocity
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Body Composition
Changes in body composition from baseline to 12 weeks and baseline to 26 weeks are measured by the waist circumference.
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Body Composition
Changes in body composition from baseline to 12 weeks and baseline to 26 weeks are measured by bioelectrical impedance.
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Body Composition
Changes in body composition from baseline to 12 weeks and baseline to 26 weeks are measured by body mass index.
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Depression
Changes in depression from baseline to 12 weeks and baseline to 26 weeks are measured by the Beck Depression Inventory-II questionnaire
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Quality of Life - SF36
Changes in quality of life from baseline to 12 weeks and baseline to 26 weeks are measured by the Short Form-36.
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Quality of Life - HeartQoL
Changes in quality of life from baseline to 12 weeks and baseline to 26 weeks are measured by the HeartQoL questionnaire
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Exercise Adherence
Changes in exercise adherence from baseline to 12 weeks and baseline to 26 weeks are measured by the Actigraph accelerometer
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Depression mechanisms
Changes in depression mechanisms from baseline to 12 weeks and baseline to 26 weeks are measured by plasma brain derived neurotrophic factor.
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Depression mechanisms
Changes in depression mechanisms from baseline to 12 weeks and baseline to 26 weeks are measured by plasma irisin.
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Depression mechanisms
Changes in depression mechanisms from baseline to 12 weeks and baseline to 26 weeks are measured by plasma kynurenine.
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Lipid and glucose profile
Changes in lipid and glucose profile from baseline to 12 weeks and baseline to 26 weeks are measured by plasma total cholesterol.
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Lipid and glucose profile
Changes in lipid and glucose profile from baseline to 12 weeks and baseline to 26 weeks are measured by plasma Low Density Lipoprotein
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Lipid and glucose profile
Changes in lipid and glucose profile from baseline to 12 weeks and baseline to 26 weeks are measured by plasma High Density Lipoprotein.
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
Lipid and glucose profile
Changes in lipid and glucose profile from baseline to 12 weeks and baseline to 26 weeks are measured by plasma Hemoglobin A1c
Time frame: Baseline to 12 weeks and Baseline to 26 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.