the Effect of Gut Microbiota on the Prognosis of Sepsis

Jinan University Guangzhou30 enrolled

Overview

Sepsis is a life-threatening condition that arises when the body's response to infection injures its own tissues and organs. Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. Clinically, sepsis patients with diarrhea often result in a bad prognosis. Gut microbiota consists of a complex community of microorganisms that live in the digestive tracts of animals. The gut microbiota comprises the largest and most diverse reservoir of mutualistic microorganisms associated with animals. The aims of this study is to determin the effect of gut microbiota on the prognosis of Sepsis, by using 16s pyrosequencing, comparing the blood culture result.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sepsis

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects diagnosed with sepsis * 18 years to 65 years of age Exclusion Criteria: * patients had complications such as acute cerebral infarction or acute myocardial infarction * The use of antibiotics, pro-prebiotics within 3 months * \<18 years or \>65 years * History of intestinal surgery * patients withdraw from this study

Outcomes

Primary Outcomes

Discharged from ICU

Time frame: 7 days