Not only caries but also exposure to acids can lead to loss of tooth structure. This acid-related tooth structure loss is defined as dental erosion. A relationship between dental erosion and occurence of reflux disease was shown in numerous studies. On the one hand, patients with dental erosions frequently show reflux disease. On the other hand, many - but not all - reflux patients show dental erosions. It is believed that certain salivary parameters might explain, why not all reflux patients alike are affected of dental erosions. The aim of this study is to analyze the relationship and the extent of occurrence of dental erosions and reflux symptoms, including investigation of certain salivary parameters.
Study Type
OBSERVATIONAL
Enrollment
30
Collection of saliva samples
Visual detection of BEWE-index
Visual assessment of the BEWE-(basic erosive wear examination)-index
Time frame: After removal of the probe (on second day)
Determination of unstimulated and stimulated saliva flow rate (ml/min).
Time frame: While wearing the probe at three time points over 24h: morning, noon, evening
Determination of saliva pH and buffer capacity (mol/L).
Time frame: While wearing the probe at three time points over 24h: morning, noon, evening
Determination of total protein content in saliva (g/L).
Time frame: While wearing the probe at three time points over 24h: morning, noon, evening
Determination inorganic calcium and phosphate in saliva (mmol/L).
Time frame: While wearing the probe at three time points over 24h: morning, noon, evening
Measurement of salivary enzyme activity: Protease, Kollagenase/Gelatinase, Pepsin, Trypsin, and Amylase (U/mL).
Time frame: While wearing the probe at three time points over 24h: morning, noon, evening
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