The study is designed to determine if enhanced recovery after surgery (ERAS) principles could provide benefit for pediatric patients undergoing radical surgery for Hirschsprung's Disease (HD). Half of patients will receive the ERAS program, while the other half will receive the traditional program.
Optimized peri-operative care within an enhanced recovery after surgery (ERAS) protocol is designed to reduce morbidity after surgery, resulting in a shorter hospital stay. The present study evaluated this approach in the context of radical surgery for pediatric patients with Hirschsprung's Disease(HD). Patients undergoing radical surgery for HD will be enrolled in a randomized clinical trial comparing ERAS protocol vs a control group that received standard care. The primary outcome is median length of postoperative hospital stay. The second outcomes include postoperative complications rates，gastrointestinal function recovery time，mean cost per patient，readmission rates within postoperative 30 days，and the levels of stress and inflammation marker.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
200
optimized peri-operative protocol
traditional standard protocol
The Children's Hospital Of Soochow University
Suzhou, Jiangsu, China
RECRUITINGWuxi Children's Hospital Affiliated to Wuxi People's Hospital Group
Wuxi, Jiangsu, China
RECRUITINGXuzhou CHildren's Hospital Affilated to Xuzhou Medical College
Xuzhou, Jiangsu, China
RECRUITINGmedian length of postoperative hospital day
Time frame: 30days
postoperative complications rates
Time frame: within 30 days
gastrointestinal functional recovery time
Time frame: within 30 days
mean cost per patient
Time frame: within 30 days
the readmission rates
Time frame: within 30 days
the level of stress and inflammation marker
Time frame: within 30 days
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