The study aims to investigate whether disease progression in patients with chronic heart failure (CHF) can be assessed by new biomarkers, and determine their diagnostic value. The study also intends to describe comparison of echocardiography with cardiopulmonary function test in CHF patients, and relating these cardiac functional parameters to clinical outcome.
Study Type
OBSERVATIONAL
Enrollment
1,000
Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Shanghai, Shanghai Municipality, China
RECRUITINGmain adverse cardiovascular and cerebrovascular events, MACCE
MACCE includes all-cause mortality, cardiovascular mortality, nonfatal myocardial infarction, nonfatal stroke, target lesion revascularization and HF rehospitalization
Time frame: 10 years
cardiovascular mortality
Time frame: 10 years
all-cause mortality
Time frame: 10 years
new myocardial infarction
Time frame: 10 years
new stroke
Time frame: 10 years
heart failure rehospitalization
Time frame: 10 years
quality of life
described in quality of life scores
Time frame: 10 years
worsening of renal function
either an increase of 0.3 mg/dl in serum creatinine or a 20% decrease in eGFR compared with baseline
Time frame: 10 years
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