Evaluation of Perioperative Celecoxib for Hip Arthroscopy

Northwestern University98 enrolled

Overview

Celecoxib is commonly used for perioperative pain control for certain orthopaedic procedures. It has been shown to be successful in assisting in pain control for knee arthroscopy. It has not previously been studied in hip arthroscopy. This is a double blinded randomized controlled trial to determine the efficacy of celecoxib in perioperative pain control for hip arthroscopy.

This study examines the efficacy of perioperative dose of celecoxib in pain management after hip arthroscopy. Perioperative administration of celecoxib has been shown to improve pain control after knee arthroscopy, but this has not yet been studied in the hip. In this study, patients are randomized to receive either 400mg celecoxib or placebo 1 hour prior to undergoing hip arthroscopy surgery. Postoperatively, patients are monitored for pain on the VAS scale, narcotic use, and meeting discharge criteria. The study will enroll 100 patients. Patients are approached for informed consent on the day of surgery. Pain scores, narcotic use, and time to discharge in the celecoxib group are compared to the placebo group.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Hip Labral Tears

Interventions

CelecoxibDRUG

Received 400mg celecoxib prior to surgery

placeboDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 89 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients who are undergoing a hip arthroscopy procedure at Northwestern Memorial Hospital with Dr. Michael Terry. Exclusion Criteria: * Pregnant women and any patient under the age of 18 years.

Outcomes

Primary Outcomes

Visual Analog Score for Pain (VAS) in the Immediate Post Operative Period

The pain VAS is a uni dimensional measure of pain intensity. It is a continuous scale comprised of a 0-10 pain rating. A score of 0 indicates no pain while a score of 10 would indicate extreme pain.

Time frame: Pre operative on day of surgery, immediately following OR close, 1 hr post operatively, 2 hrs post operatively

Total Narcotic Consumption in the Post Anesthesia Care Unit (PACU)

Monitored consumption of narcotic medications following surgery, measured in morphine equivalents

Time frame: duration of PACU stay,immediate post op period up to a maximum of 4 hours postoperatively

Time to Discharge Following Surgery

Total time to discharge from OR close following surgery, measured in minutes

Time frame: time from OR to discharge, up to a maximum of 6 hours postoperatively

Data from ClinicalTrials.gov

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