Clinical Study to Assess Efficacy and Safety of a New Compression System in the Management of Venous Leg Ulcers

Inclusion Criteria: * Inpatients or outpatients. * Agreeing to wear a multilayer compression system throughout the study period. * Presenting with an active venous leg ulcer: Duration between 1-24 months (whether a new ulcer or a recurrent ulcer); Surface area between 2-50 cm2; Venous, superficial or post-thrombotic ulcer confirmed by Doppler ultrasonography (dated within six months). * With ankle circumference between 18-25 cm to allow the laying of the compression system. * Able to follow the study instructions. * Having read the information sheet and dated and signed the informed consent form. * Covered by a health insurance system. Exclusion Criteria: * Scheduled surgery for the ulcer during the 16 weeks following inclusion. * Clinical superinfected ulcer not controlled oral antibiotics. * Malignant ulcer. * Ulcer surface totally covered with dry fibrinous tissue or covered with black necrotic plaque on over 10% of its surface. * Deep Vein Thrombosis within the last 3 months. * Corticosteroids treatment (equivalent to more than 10 mg per day of prednisolone) ongoing or planned during the study. * Radiotherapy, chemotherapy or immunosuppressive therapy ongoing or planned during the study. * Erysipelas and lymphangitis. * Lower extremity arterial disease or microangiopathy (Ankle Brachial Pressure Index \<0.8 or\> 1.3). * Uncontrolled non-insulin dependent diabetes (HbA1c\> 8%). * Insulin-dependent diabetes. * Confined to bed. * With any uncontrolled severe and progressive disease. * With a known or suspected hypersensitivity to any of the components of the study devices. * Who had participated in a previous clinical study within the past 3 months. * Pregnant women.