This pilot clinical trial studies how well an iPad-based cognitive rehabilitation program works in improving quality of life in patients with grade II-III glioma. An iPad-based cognitive rehabilitation program may help to increase patients cognitive function and quality of life, and may provide doctors with valuable information for optimizing care of patients with brain tumors.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
11
All patients will receive baseline neurocognitive and quality of life testing, followed by 3 months of the iPad-based intervention. At the end of the baseline visit, subjects will be lent an iPad to take home (or will be assisted in the installation of the ReMind app on their personal iPad) and instructed in the use of the ReMind app (and more basic iPad skills, if necessary). Subjects will review the intervention schedule (approximately 3 hours per week). Testing will be repeated 3 months after the baseline visit (i.e., immediately after the intervention) and 9 months after the baseline visit (i.e., 6 months after completion of the intervention), both time-points including a new MRI.
University of California, San Francisco
San Francisco, California, United States
Number of subjects who complete the intervention
Subjects who complete all of the intervention exercises (approximately 36 hours of intervention).
Time frame: At 3 months after start of training
Patient-reported ease of use
Questionnaire based measure of ease of use as a measure of feasibility.
Time frame: At 3 months after start of training
Patient-reported user satisfaction
Questionnaire based measure of user satisfaction as a measure of feasibility.
Time frame: At 3 months after start of training
Change in attention
Evaluation of visual attention on the NIH Toolbox Flanker Inhibitory Control and Attention Test. The attention score ranges from 0 to 10 (10 = best performance)
Time frame: At baseline, 3 months past training start, 9 months past training start
Change in working memory
Evaluation of working memory using the NIH Toolbox List Sorting Working Memory Test. Higher scores on each of these indicate higher levels of working memory.
Time frame: At baseline, 3 months past training start, 9 months past training start
Change in Quality of Life
Measurement of general quality of life (QOL) using Functional Assessment of Cancer Therapy-Brain (FACT-Br), a multi-item questionnaire. Higher ratings suggest higher QOL.
Time frame: At baseline, 3 months past training start, 9 months past training start
Improvement on neurocognitive testing
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Improvement on neurocognitive testing as measured by the NIH Toolbox assessment after the intervention.
Time frame: At baseline, 3 months past training start, 9 months past training start
Subjective assessment of cognitive symptoms will be assessed
Subjective assessment of cognitive symptoms using the Functional Assessment of Cancer Therapy: Cognitive Function (FACT-Cog) questionnaire
Time frame: At baseline, 3 months past training start, 9 months past training start