Clinical Outcomes of Preoperative and Postoperative Rehabilitation in the Patients With HBP Malignancy

Inclusion Criteria: * \>18 years old or \<80 years old * ECOG 0-2 * resectable HBP malignancies or premalignant lesions which should be required GI resection and anastomosis * open surgery * no distant metastasis * no functional disturbance in bone marrow; WBC at least 3,000/mm3 or absolute neutrophil count at least 1,500/mm3, Platelet count at least 125,000/mm3 * no functional disturbance in liver; AST less than 5 times upper limit of normal * no function disturbance in kidney; Creatinine no greater than 1.5 times upper limit of normal * informed consent Exclusion Criteria: * distant metastasis (+) or recurred HBP tumor * active or uncontrolled infection * alcohol or other drug addiction * already enrolled patient in other study which affect this study * pregnant or the possibility of pregnancy (+) * uncontrolled cardiopulmonary disease * moderate to severe comorbidity which affect on the quality of life and nutritional status (liver cirrhosis, end stage renal disease, heart failure, etc.) * previous history of major gastrointestinal surgery (gastrectomy, colectomy, etc.) * previous history of neurological or musculoskeletal diseases which is impossible to allow investigator's order