In this study, based on the hypothesis that dexmedetomidine administered intraoperatively for sedation can reduce postoperative pain than that of propofol, the investigators examined the ability of dexmedetomidine to reduce postoperative pain in in patients undergoing the total knee arthroplasty.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
48
Intraoperative sedation using dexmedetomidine
Intraoperative sedation using propofol
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
Visual analogue scale
Postoperative pain score at postoperative 24 hours
Time frame: Postoperative 24 hours
Rescue analgesics
Amount of rescue analgesics administered during 24 hours postoperatively
Time frame: Postoperative 24 hours
Rescue analgesics
Amount of rescue analgesics administered during 48 hours postoperatively
Time frame: Postoperative 48 hours
Visual analogue scale
Postoperative pain score at postoperative 48 hours
Time frame: Postoperative 48 hours
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