Primary aim of the TURKAPNE (The Turkish Sleep Apnea Database) study is to generate a cross-sectional nationwide database to define clinical and polysomnographic characteristics of the sleep apnea patients in Turkey. Associations of phenotypes of sleep apnea patients with metabolic and cardiovascular diseases as well as risk for traffic accidents will be explored as secondary aims. Impact of treatment of sleep apnea on metabolic and cardiovascular complications as well as compliance with positive airway pressure treatment will be further explored longitudinally.
All subjects undergoing sleep study for suspicion of obstructive sleep apnea will be registered in a web-based national database regarding: * Anthropometric data, educational status, driving licence, * Smoking and alcohol use * Comorbidities, and drug use * Questionnaires, excessive daytime sleepiness * Polygraphic and polysomnographic findings * Blood pressure measurements * If taken, blood glucose, lipids and other biochemical markers * If measured, lung function test results * If measured, echocardiography findings * Follow-up data regarding treatment modality and compliance
Study Type
OBSERVATIONAL
Enrollment
10,000
Treatment of OSA with PAP
Treatment of OSA with IOD
Uvuloplasty
No active intervention
Koç University Hospital
Istanbul, Turkey (Türkiye)
RECRUITINGMetabolic and cardiovascular diseases in obstructive sleep apnea phenotypes
The association of sleep apnea severity indices such as Apnea-Hypopnea Index and Oxygen Desaturation Index during Rapid Eye Movement (REM) sleep and non-REM sleep with self-reported diabetes mellitus and cardiovascular diseases will be explored.
Time frame: Up to three years
Sex differences in obstructive sleep apnea phenotypes
Possible sex differences in REM-dependent sleep apnea, positional sleep apnea and its association with metabolic and cardiovascular diseases will be explored
Time frame: Up to three years
Adherence to positive airway pressure treatment in obstructive sleep apnea
Predictors of adherence to positive airway pressure treatment (defined as device usage at least 4 hours of night during at least 70% of study period) in obstructive sleep apnea
Time frame: Through study completion, an average of 7 years
Incidence of cardiovascular diseases and mortality
Number of patients who have died or developed cardiovascular diseases
Time frame: Through study completion, an average of 7 years
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