Pharmacokinetics Study of Azilsartan Tablets in Chinese Healthy Volunteers

Inclusion Criteria: 1. Subjects in all groups will be adult females or adult males between 18 and 45 (inclusive) years of age, the year age difference between each subject cannot be more than 10. 2. Body mass index (BMI) within the range 19\~25kg/m2 (inclusive). BMI=weight (kg)/height(m)2。 3. Subjects are eligible to participate if the results of physical examination （height, weight, respiration, pulse, blood pressure, thorax, abdomen, etc） and laboratory examination (blood routine examination, urine routine test, blood chemistry test, infectious disease screening, etc) are normal, the tests above will be conducted to all the subjects before the trial initiating. The results of ECG and chest X-ray are normal or slightly abnormal without clinical significance. 4. Subjects should not have history of cardiovascular disease, liver disease, renal disease, digestive disease, psychiatric disease, neuropathy disease, etc. 5. Subjects who do not have allergic history of Angiotensin Receptor Blockers, the other drugs and biological agents. 6. Subjects who are not addicted to smoking and alcohol and without the other bad habits. 7. Subjects have not participated in other clinical trial and donated blood within 3 months prior to this trial, 8. Subjects have well known the nature, significance, possible benefits, inconveniences and potential risks before participating in this trial and understood the trial process. Subjects are voluntary to participate in this trial. Exclusion Criteria: 1. Subjects who have abnormalities with clinical significance in physical examination, laboratory examination, 12-lead ECGs, chest X-ray. 2. Subjects with history of orthostatic hypotension, gastrointestinal disease (such as gastric ulcer, gastritis, etc), renal disease (such as nephritis, nephropyelitis, etc), or cardiovascular, respiratory, neurological, psychotic, haematological, endocrine or the other disorders. 3. Subjects with allergic constitution with history of sensitivity to Angiotensin Receptor Blockers or a history of the other drugs and biological agent. 4. Systolic blood pressure (SBP) \<90mmHg or \>140mmHg, and/or diastolic blood pressure (DBP) \<50mmHg or \>90mmHg. Subjects with orthostatic hypotension (at screening, symptomatic or asymptomatic orthostatic hypotension is defined as: subject lying down comfortably for 5 minutes, the blood pressure which is recorded at 5 min considered to be the baseline. The time point of subject stands is considered to be the onset time. Orthostatic hypotension is diagnosed by a rise in systolic blood pressure of 20mmHg or more, or a decrease in diastolic blood pressure of 20mmHg or more, when standing with arms relaxing). 5. Vegetarian. 6. Subjects who plan to bear children in 6 months. 7. History of alcohol abuse in the last 6 months prior to screening defined as an average weekly intake of greater than 14 unit (one unit is equivalent to 360ml of beer or 45ml of spirits with 40% alcohol content or 150 ml of wine). History of smoking \>5 cigarettes a day in the last 6 months prior to screening. 8. History of administrating any drugs that will effect this trial. Subjects who have participated in donation of blood or any drug clinical trial(as subjects) in the last 3 months, or are taking any other drugs. 9. Hepatitis B patients, or Hepatitis C patients, or hepatitis C carrier, or subjects with immunodeficiency, or positive HIV antibody results, or positive syphilis antibody results. 10. 72 hours prior to randomization, subjects with history of special diet (includes grapefruit, xanthine diet, chocolate, caffeinated coffee or tea, or any other caffeinated beverages) or strenuous exercise, or with the other factors that will effect the absorption, distribution, metabolism and excretion. 11. Subjects who took prescription drugs 2 weeks before study. 12. Subjects who, in the opinion of the investigators, should not participate in the study.