Safety of Chlamydia Vaccine CTH522 in Healthy Women Aged 18 to 45 Years

Inclusion Criteria: 1. Is a healthy female between 18 and 45 years of age on the day of first trial vaccination 2. Has provided signed informed consent 3. Is willing and likely to comply with the trial procedures 4. Is prepared to grant authorised persons access to their medical record 5. Willing to use acceptable contraceptive measures\* during the trial (2 weeks before and 2 weeks after the trial) * Heterosexually active female capable of becoming pregnant must (in addition to requiring male partner to use condoms) agree to use hormonal contraception, or to complete abstinence, from at least 2 weeks before the first vaccination until at least 2 weeks after the last. (Note: Periodic abstinence \[e.g. calendar, ovulation, symptothermal, post-ovulation methods\] and withdrawal and intrauterine device or intrauterine hormone releasing system and progestogen-only oral hormonal contraception, where inhibition of ovulation is not the primary mode of action, are not acceptable methods of contraception) Exclusion Criteria: 1. Has confirmed history of Pelvic Inflammatory Disease or significant gynaecological diseases 2. Is positive for C. trachomatis (PCR) 3. Is positive for gonorrhoea (urine), HIV, Hepatitis B/C, syphilis (blood) 4. Has a positive pregnancy test 5. Has a significant active disease - such as cardiac, liver, immunological, neurological, psychiatric; or clinically significant abnormality of haematological or biochemical parameters. 6. Has BMI of 35 kg/m2 or greater 7. Is currently participating in another clinical trial with an investigational or noninvestigational drug or device 8. Has received, or plans to receive, an active immunisation within 14 days of the start of the trial or any of the immunisation visits in this trial 9. Is currently receiving treatment with immunosuppressive agents e.g. oral, inhaled, nasal or injected corticosteroids. (Topical steroids are allowed, unless applied to the IM injection site.) 10. Is using an intrauterine device 11. Has a condition which in the opinion of the investigator is not suitable for participation in the trial 12. Known or confirmed allergy to any of the vaccine constituents -