Lymphadenectomy for Pancreatic Head Cancer: Standard or Extended?

Ruijin Hospital230 enrolled

Overview

The purpose of this study is to compare outcomes of patients undergoing standard or extended lymphadenectomy in pancreaticoduodenectomy for pancreatic cancer

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

230

Conditions

Pancreatic Ductal Adenocarcinoma

Interventions

Pancreaticoduodenectomy with Standard lymphadenectomyPROCEDURE

Pancreaticoduodenectomy：child's digestive reconstruction standard lymphadenectomy: No 5 6 8a 12b1 12b2 12c 13a 13b 14a 14b 17a 17b

Pancreaticoduodenectomy with Extended lymphadenectomyPROCEDURE

Pancreaticoduodenectomy：child's digestive reconstruction extended lymphadenectomy: No8p 12a 12p 14c 14d 16

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Pathologic diagnosis of pancreatic ductal adenocarcinoma * Signed the informed consents Exclusion Criteria: * Pathologic diagnosis of other pancreatic cancers * Pre-operative anti-cancer treatment * Recurrence patients * Patients with contraindication(hepatic/ respiratory/ renal dysfunction, etc ) * Pre operative exam: Total bilirubin more than 250µmol/L * AJCC stage IV * Operation non radical

Locations (1)

Shanghai Ruijin Hospital

Shanghai, Shanghai Municipality, China

Outcomes

Primary Outcomes

All-cause mortality

Time frame: 3yrs post-operation

Secondary Outcomes

all-cause mortality

Time frame: 1yr post-operation

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.