Perioperative Use of a Selective COX2 Inhibitor in Patients Undergoing Elective Colorectal Surgery: the Effect on Post-operative Bowel Motility and Post-operative Pain

Inclusion Criteria: * Patients between the age of 18 and 80 * Patients planned for elective colorectal surgery with primary anastomosis * ASA score of 1-3 * Patients that are able to sign an informed consent and comply with the protocol Exclusion Criteria: * Patients with inflammatory bowel disease * Patients that require emergency surgery * Patients with renal failure, measured by Creatinine level \> 1.5 mg/dL (\>106.1 micro mol/l) * Patients with significant liver failure (known cirrhosis, Bilirubin level\>2 mg/dL or 34.2 µmol/L) * Patients with known allergy to any medication from the non-steroidal anti-inflammatory drug group. * Patients treated chronically with any type of COX inhibitor. * Patients treated with NSAIDS including Aspirin 7 days prior to the date of surgery. * Patients with active peptic disease * Patient expected to take muscle relaxants, tricyclic antidepressants, tranquilizers, sedatives, hypnotics or neuroleptics in the postoperative period * Patient with dysphagia or that have a difficulty swallowing capsules or tablets, or is unable to tolerate oral medication * Pregnant / lactating women. * Patients participating in any other interventional clinical trial