Statin Therapy In Patients With Vasospastic Angina

Phase 4WithdrawnNCT02790528

Seung-Jung Park

Overview

The purpose of this study is to evaluate whether statin is effective in the treatment of vasospastic angina.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Conditions

Angina Pectoris, Variant Statins, HMG-CoA

Interventions

AtorvastatinDRUG

20mg QD

PlaceboDRUG

Placebo drug will be administered.

Eligibility

Sex: ALLMin age: 19 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 19 and more * Vasospastic angina * LDL less than 160mg/dl * Written consent Exclusion Criteria: * Coronary artery stenosis more than 50% or ischemic coronary disease * History of percutaneous coronary intervention * Cerebrovascular diseases or peripheral * Dyslipidemia required statin therapy * Heart failure, arrhythmogenic right ventricular dysplasia, hypertrophic cardiomyopathy, akinesia or aneurysm on left ventricular wall, anomaly of coronary artery * NYHA III and IV * Arrhythmia * Primary cardiac electrical diseases * Cardiac pacemaker or implantable defibrillator * Pregnancy or breast feeding * Life expectancy less than 2 years

Locations (1)

Asan Medical Center

Seoul, Songpa-gu, South Korea

Outcomes

Primary Outcomes

The Composite Event of all-cause death, myocardial infarction, angina-related hospitalization

The number of events with the first occurrence of a composite event(all-cause death, myocardial infarction, angina-related hospitalization)

Time frame: 3 years

Secondary Outcomes

all-cause death

Time frame: 3 years

cardiac death

Time frame: 3 years

cardiac arrest

Time frame: 3 years

myocardial infarction

Time frame: 3 years

angina-related hospitalization

Time frame: 3 years

Composite event of death or myocardial infarction

Time frame: 3 years

Composite event of cardiac death or myocardial infarction

Time frame: 3 years

statin-related complications

event rate of statin-related complications

Time frame: 3 years

Data from ClinicalTrials.gov

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