Comparison of Laboratory Changes, Food Intake and Metabolic Profile in Patients With Obesity and Type2 Diabetes Mellitus: Before, During and After Taking AphoelineBrake

Inclusion Criteria: * Age ≥21 years * Diagnosis of T2DM * Metformin as first line treatment * HbA1c ≥7 * Calculated HOMA-IR ≥3.0, * BMI 25-45 * Triglyceride level ≥ 2.26 mmol/L Exclusion Criteria: * Age \<21 years of age * BMI ≤ 25 * Pregnant * Subjects on chronic nonsteroidal anti-inflammatory drugs or systemic corticosteroids. * Subjects treated with Liraglutide (Victoza®). * Renal, hepatic or cardiac failure. * Subjects with a significant clinical illness within a month before the first administration of Aphoeline Brake™ * Subjects diagnosed with Irritable Bowel Syndrome. * Subjects diagnosed with Ulcerative Colitis or Crohn's disease. * History of significant gastrointestinal disease. * Poor venous access. * Poor likelihood to adhere with study procedures, as documented during the MyFitnessPal procedures prior to use of Aphoeline Brake™