Acute kidney injury (AKI) is common, serious and expensive.It is associated with significant mortality, morbidity and increased length of hospital stay.To improve clinical outcomes of AKI by early detection and timely referral to the renal,the investigators developed an electronic alert system which identifies all cases of AKI occurring in patients over 18 years.The system was also designed to collect data on AKI incidence one of the biggest tertiary hospital in China.
A prospective, randomly controlled cohort study will be conducted agmong the patients with AKI who are detected by the use of AKI sniffer. The investigators chose to assess all inpatient serum creatinine results using a combination of "KDIGO" criteria. The investigators randomly divided the patients into two groups: 1. Usual care : patients will receive standard clinical care by the primary physicians 2. AKI alert : an AKI alert will be sent to the the doctor in charge. Our team of kidney experts would give a suggestion if the the doctor in charge issue consultation applications.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Enrollment
2,000
Nephrology Dept,Guangdong General Hospital
Guangzhou, Guangdong, China
Adverse events during hospitalization
cardiac shock/ need for intensive care/ cardiopulmonary resuscitation/ cardiac death/ death
Time frame: from start of AKI to discharge,up to 4 weeks
Incidence of cardiovascular disease and its occurrence time followed up for 1 years
heart failure/ acute coronary syndrome/ readmission/cardiac readmission/ cardiovascular intervention or surgery
Time frame: One year after discharge
The AKI outcome and its occurrence time followed up for 1 years
AKI recovery/stop renal replacement therapy
Time frame: One year after discharge
AKI recovery/stop renal replacement therapy
Glomerular filtration rate decreased/ new occurrence proteinuria/ original proteinuria aggravation
Time frame: from start of AKI to discharge,up to 4 weeks
Proportion of nephrology referral
Time frame: from start of AKI to discharge,up to 4 weeks
Diagnostic rate of AKI at discharge
Time frame: from start of AKI to discharge,up to 4 weeks
Follow-up rate after discharge
Time frame: One year after discharge
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