The purpose of this study is to determine if when one eats protein can change how the body uses food for energy. Researchers will also test if eating a high protein breakfast can change one's craving for snack foods.
The purpose of this study is to determine if consuming 30 g of high-quality protein at each meal can increase fat utilization and shift between-meal snack choices. While the benefits of high-protein diets are well known, little is known about the optimal amount of protein that should be eaten at each meal. Most Americans eat little protein at breakfast and lunch and most of their protein at the evening meal. Current guidelines for protein are based on body weight; however, recent evidence indicates that absolute amounts of protein at each meal are needed to maintain metabolically active fat-free mass. This suggests that a more even protein consumption pattern across daily meals may positively influence energy metabolism. In addition, recent evidence indicates that protein may reduce activity in the food reward areas of the brain. This suggests that protein may influence between-meal snacking by decreasing the relative reinforcing value (RRV) of highly rewarding snack foods. The RRV of a food is an empirical measure of its motivating value and energy-dense foods are highly reinforcing, especially for obese individuals. This study will be the first to investigate the role of the daily distribution of protein intake on energy metabolism and modifying snacking behavior.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
53
5 day intake of even protein 3 day rotating menu.
5 day intake of skewed protein 3 day rotating menu.
USDA Grand Forks Human Nutrition Research Center
Grand Forks, North Dakota, United States
Fat, carbohydrate, and protein utilization
The effect of consuming two patterns of daily protein intake on the use of fat, carbohydrate and protein for energy.
Time frame: 4 hours after meal consumption
Relative reinforcing value (RRV) of energy-dense snack foods
The effect of consuming a high-protein or a low-protein breakfast on the RRV of energy-dense snack foods to a healthy snack food alternative.
Time frame: 2 hours after breakfast consumption
Peripheral neurotransmitter metabolites
The effect of consuming a high-protein or low-protein breakfast and an energy-dense snack food on dopamine and serotonin metabolite plasma concentrations.
Time frame: 2 hours
Psychoactive Effect Questionnaire
The effect of consuming a high-protein or low-protein breakfast and an energy-dense snack food on the number of positive responses on the Psychoactive Effects Questionnaire.
Time frame: 2 hours
Satiety visual analog scales
The effect of consuming two patterns of daily protein intake on subjective measures of satiety.
Time frame: 4 hours after meal consumption
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