Investigators will collect blood specimens from the participating patients and then blood samples will be centrifuged in order to collect platelet-rich plasma which is going to be injected in the atrophic acne scars. A split-face design is going to used in this randomized controlled trial. In the control side of the face, micro-needling to the skin will occur using a specific tool (Dermapen).
Atrophic acne scar is a common problem with a challenging treatment. Platelet-rich plasma (PRP) is an autologous preparation of platelets in concentrated plasma that may be beneficial in the treatment of atrophic acne scars by promoting collagen deposition. Skin needling is a technique that uses a sterile micro needles to puncture the skin and release growth factors. The combination of skin needling and PRP could enhance the efficacy of both modalities.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
50
This Platelet-Rich Plasma will be taken from each patient and is going to be used in the treatment of atrophic acne scars
Micro-needling will be applied on the acne scars in one side of the face.
Department of Dermatology and Venereology
Damascus, Syrian Arab Republic, Syria
Change in Scar Appearance
Time frame: Scar Appearance will be assessed at: T1; one day (wihtin 24 hours) before the application of the intervention(s); and T2: after three months of applying the intervention(s).
Patients' Satisfaction
The assessment will be based on a questionnaire
Time frame: This is going to be assessed six months following the application of the intervention and the active comparator
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