Effect of Reslizumab in Chronic Rhinosinusitis

Inclusion Criteria: 1. Written informed consent 2. Willingness and ability to comply with the requirements of the study 3. Female or male patients ages 18-75 at the time of screening 4. A diagnosis of chronic rhinosinusitis according to the clinical practice guideline (update) of the American academy of otolaryngology - head and neck surgery 5. Elevated blood eosinophils 6. Significant findings on computed tomography (CT) scan Exclusion Criteria: 1. Unable to sign informed consent form 2. A woman that is pregnant or nursing a child 3. Known hypersensitivity to Reslizumab 4. Active cigarette smoking in the year prior to screening 5. Known underlying immunodeficiency 6. History of alcohol or drug abuse in the year prior to screening Other criteria may apply. Please contact the investigator for more information