HYPID-2 study is an extension of HYPID study (NCT01443598) : HYPID-2 is also an observational and prospective study of patients with interstitial lung disease and pre capillary hypertension diagnosed by right heart sided catheterization. It concerns only incident patients (i.e patients included within 6 months after PH diagnosis) whereas HYPID concerned prevalent and incident cases. The primary aim is the same than HYPID : identify prognostic factors
Pre capillary pulmonary hypertension (PH) may be present in patients with diffuse interstitial lung disease. In this context, PH represents an important factor of morbidity and mortality for these patients. As in HYPID, the main purpose of HYPID-2 is to determine predictive factors of mortality within this cohort of incident patients (i.e patients included within 6 months after PH diagnosis). In order to reach that aim,the study includes an evaluation based on exams conducted for the routine follow-up of incident patients. Each incident patient will be followed during 2 years at least.
Study Type
OBSERVATIONAL
Enrollment
210
Louis Pradel Hospital (Bâtiment A4)
Lyon, Bron, France
Overall survival
Determine predictive factors of mortality
Time frame: 2 years
Progression-free survival
Time to death or 10% decline in FVC
Time frame: 2 years
Response to therapy
Proposition of patients with 10% or more decline in PVR
Time frame: 2 years
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