Effect of Cis-9-cetylmyristoleate in Sub-healthy Subjects Presenting With Knee Joint Pain

Inclusion Criteria: * sub-healthy persons \>18 years of age and knee joint pain with a 0-10 numerical rating scale (NRS) pain score ≤ 4. Exclusion Criteria: * current medication use related to arthritis; * current use of FAC containing products; * clinical or radiological diagnosis as moderate degree arthritis accompanied by peri-articular spur formation, irregular joint margin, and/or subchondral cyst; * previous history of knee surgery; * pregnant, breastfeeding, or practicing contraception with reliable methods, or not accepting our guidelines during the research periods; * major pain other than knee joint pain; * current treatment of gastritis or gastric ulcer; * abnormal screening laboratory results; * major cardiac, renal disease, or disability that could affect adverse effect assessment or interfere with study completion when enrolled; * history of major procedures or operations that might affect study results; * enrollment in another clinical trial or human application testing; and * judged as unsuitable for human application testing.