Emotional Brain Processes in Recreational Cannabis Users

University of Electronic Science and Technology of China50 enrolled

Overview

This fMRI study investigates neural correlates of emotion regulation, emotion processing and craving in recreational cannabis users.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Recreational Cannabis Use

Interventions

fMRIOTHER

Eligibility

Sex: MALEMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Recreational cannabis use * 72 hours of abstinence Exclusion Criteria: * neurological disorders * psychiatric disorders according to DSM-4

Outcomes

Primary Outcomes

fMRI neural correlates of emotional brain processes in recreational cannabis users after 72 hours of abstinence

Activation patterns in brain regions known to be involved in emotional processing and to be altered by cannabis use (e.g. striatum, prefrontal cortex, insula, ACC)

Time frame: one time point = fMRI assessment after 72 hours of abstinence

Secondary Outcomes

Ratings of subjective experience (affect, craving)

Time frame: one time point = during fMRI assessment after 72 hours of abstinence

Data from ClinicalTrials.gov

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