The aim of this fMRI study is to investigate neural indices of relapse in cannabis dependence. The development and maintenance of drug addictions have been associated with deficits in cognitive control, craving and impaired stress regulation. Therefore, neural markers of brain processes underlying the beforementioned components will be studied. Subsequent follow-up drug use interviews will reveal associations between relapse in cannabis dependence and alterations in brain networks of cognitive control, craving and stress.
Study Type
OBSERVATIONAL
Enrollment
75
University of Bonn
Bonn, North Rhine Westfalia, Germany
RECRUITINGfMRI neural activation patterns of emotional processing
Activation patterns associated with emotion processing, emotion regulation, craving and stress are determined in addicted cannabis users compared to non-using matched control subjects
Time frame: one time point = fMRI assessment after minimum 24 hours of abstinence
Timeline Followback Interviews
Association between fMRI correlates and drug use during follow up preiod as predictor for relapse
Time frame: one time point = 12 months after fMRI data acquisition
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